Duocarmycin A, as a chemotherapeutic agent, results in HLC-2 cells typically apoptotic changes.

Procaspase-3    Caspase-9    Duocarmycins

507.49

C₂₆H₂₅N₃O₈

118292-34-5 

1. Hirota M, et al. Distamycin A enhances the cytotoxicity of duocarmycin A and suppresses duocarmycin A-induced apoptosis in human lung carcinoma cells. Int J Biochem Cell Biol. 2007;39(5):988-96.

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