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- 产品名称： Furimazine
- 产品货号： CS15359
- 货期： 现货
- 价格与订购： 2400
- 数量：
库存： 5
- 规格： 1mg
- 产品信息
- 如何订购
货号（Catalog No.）
CS15359
别名
PBI 3939
纯度(Purity）
97.57%
产品描述(Description)
Furimazine is an imidazopyrazinone substrate. NanoLuc (Nluc) paired with Furimazine produced 2.5 million-fold brighter luminescence in mammalian cells relative to Oluc-19 with Coelenterazine.
体外活性
Furimazine is a Coelenterazine analogue. Measurement of luminescence intensity from cells expressing Nluc reveals that maximal signal is attained at about 10-20 μM Furimazine[1]. The apparent Km for purified NanoLuc (Nluc) using either Furimazine or Coelenterazine is ~10 μM, while the maximum luminescence (i.e., apparent Vmax) is ~30-fold higher for Furimazine than for native Coelenterazine.
分子式
C24H19N3O2
分子量
381.435
参考文献
[1]Hall MP, et al. Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol. 2012 Nov 16;7(11):1848-57.
储存和溶解度
DMSO:100 mg/mL (262.17 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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