![](/storage/0000/4c9c820779b2e8f108d7ff1618e64f43.jpg)
浏览量: 66
- 产品名称: Anti NFE2L2(D29G) Mouse Monoclonal Antibody
- 产品货号: CST26331
- 货期: 现货
- 价格与订购: 4800
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
Catalog Number
CST26331
Gene Symbol
NFE2L2, NRF2
iconicon
Description
Anti NFE2L2(D29G) Mouse Monoclonal Antibody
Background
NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress.
Immunogen
A synthetic peptide from the internal region of NFE2L2 which includes the mutation of D29G, human origin.
Applications
ELISA, WB, IHC
Recommended Dilutions
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration
1 mg/ml
Host
mouse
icon
Format
Liquid
Clonality
Monoclonal
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
Recognizes D29G mutant, but not wild-type NFE2L2 of vertebrates.
Immunoprecipitation/Western Blot
![](/storage/0000/4876c0dc13384d9580a48ec506478e43.jpg)
Western blot analysis of recombinant NFE2L2(D29G) and wildtype proteins. Purified His-tagged NFE2L2(D29G) protein (lane2) and corresponding wild-type protein (lane1) were blotted with Anti NFE2L2(D29G) monoclonal antibody (Cat. #26331).
icon
Immunofluorescence:
![](/storage/0000/c3b0987d2029e7d89ab817a545a7960f.jpg)
Immunofluorescence of cells expressing NFE2L2 proteins with Anti NFE2L2(D29G) antibody. HEK293T cells were transfected with pCDNA3-GFP NFE2L2(WT) plasmid (left column) or pCDNA3-GFP NFE2L2(D29G) plasmid (right column), then fixed and stained with Anti NFE2L2(D29G) monoclonal antibody (Cat. #26331).
iconicon
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
iconiconicon
Note
For Research Use Only.