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  • 产品名称: Research Grade Gemtuzumab ( 吉妥珠单抗 )
  • 产品货号: CSD00011
  • 货期: 现货
  • 价格与订购: 2480
  • 数量:
    库存: 100
  • 规格: 100μg
  • 产品信息
  • 如何订购
    货号(Catalog No.)
    CSD00011
    通用名INN
    Gemtuzumab
    纯度(Purity)
    >95%
    电泳图(SDS-PAGE image)
    浓度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    产品描述(Description)
    Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative,a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp.calichensis.Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody Label.The antibody is specifically directed against the CD33 antigen present on leukemic myeloblasts in most patients with acute myeloid leukemia (AML).By binding to the CD33 antigen on tumors,the cytotoxic agent blocks the growth of cancerous cells and causes cell death.
    别名(Alternative names)
    CDP-771,CMA-676 (ADC),WAY-CMA-676,gemtuzumab ozogamicin,hP67.6 (naked),hP67.6-calicheamicin (ADC)
    靶点;物种(Specificity target name;species)
    CD33[Homo sapiens]
    种类(Species)
    Humanized
    受体鉴定(Receptor identification)
    IgG4-kappa
    分子量(MV)
    151500.00 Da
    CAS
    220578-59-6
    存储条件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .