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  • 产品名称: H3B-8800
  • 产品货号: CS110572
  • 货期: 现货
  • 价格与订购: 1200
  • 数量:
    库存: 100
  • 规格: 1mg
  • 产品信息
  • 如何订购
    生物活性
    H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].
    Cas 号
    1825302-42-8
    分子量
    555.71
    Formula
    C31H45N3O6
    纯度
    98%
    性状
    固体
    颜色
    Yellow to orange
    运输条件
    Room temperature in continental US; may vary elsewhere.
    储存条件
    store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 6 months ,-20°C for 1 month
    参考文献
    [1]. Seiler M, et al. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nat Med. 2018 May;24(4):497-504.
    Note
    For research use only.