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- 产品名称: Research Grade Basiliximab ( 巴利昔单抗 )
- 产品货号: CSD00076
- 货期: 现货
- 价格与订购: 2480
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
货号(Catalog No.)
CSD00076
通用名INN
Basiliximab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent,specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes.It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor.This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney.
别名(Alternative names)
CHI621
靶点;物种(Specificity target name;species)
IL2RA/CD25[Homo sapiens]
种类(Species)
Chimeric
受体鉴定(Receptor identification)
IgG1-kappa
分子量(MV)
143801.3 Da
CAS
179045-86-4
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .