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- 产品名称: Research Grade Denosumab ( 地舒单抗 )
- 产品货号: CSD00157
- 货期: 现货
- 价格与订购: 2480
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
货号(Catalog No.)
CSD00157
通用名INN
Denosumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010.
别名(Alternative names)
AMG162
靶点;物种(Specificity target name;species)
TNFSF11/CD254[Homo sapiens]
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
IgG2-kappa
分子量(MV)
144700.00 Da
CAS
615258-40-7
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .