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- 产品名称： Research Grade Raxibacumab ( 雷昔库单抗 )
- 产品货号： CSD00167
- 货期： 现货
- 价格与订购： 2480
- 数量：
库存： 100
- 规格： 100μg
- 产品信息
- 如何订购
货号（Catalog No.）
CSD00167
通用名INN
Raxibacumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
别名(Alternative names)
IDEC-C2B8
靶点;物种(Specificity target name;species)
Anthrax protective antigen [Bacillus anthracis]
活性研究（体外/体内研究）(Activity in vitro)
In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC <1 μg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 μg/ml). A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don't significantly affect the PA-824 MICs (≤ 0.25 μg/ml).
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
IgG1-lambda
分子量(MV)
142844.53 Da
CAS
565451-13-0
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
产品销售：
E - mail ：
邮 编：
Amily
