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- 产品名称: Research Grade Aselizumab ( 阿塞珠单抗 )
- 产品货号: CSD00177
- 货期: 现货
- 价格与订购: 2480
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
货号(Catalog No.)
CSD00177
通用名INN
Aselizumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
别名(Alternative names)
HuDreg-55
靶点;物种(Specificity target name;species)
SELL/CD62L [Homo sapiens]
活性研究(体外/体内研究)(Activity in vitro)
Dexamethasone (Hexadecadrol) regulates several transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, leading to the activation and repression of key genes involved in the inflammatory response.
Dexamethasone potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells with EC50 of 2.2 nM. Dexamethasone (EC50=36 nM) induces transcription of the β2-receptor is found to correlate with glucocorticoid receptor (GR) DNA binding and occurred at 10-100 fold higher concentrations than the inhibition of GM-CSF release. Dexamethasone (IC50=0.5 nM) inhibits a 3×κB (NF-κB, IκBα, and I-κBβ), which is associated with inhibition of GM-CSF release.
种类(Species)
Humanized
受体鉴定(Receptor identification)
IgG4-nd
CAS
395639-53-9
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .