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- 产品名称： Recombinant SARS-CoV-2 (2019-nCoV) NSP1
- 产品货号： CSEP02461COV
- 货期： 现货
- 价格与订购： 2880
- 数量：
库存： 10
- 规格： 100μg
- 产品信息
- 如何订购
产品名称（Product name）
Recombinant SARS-CoV-2 (2019-nCoV) NSP1
货号（Catalog#）
CSEP02461COV
描述（description）
Recombinant SARS-CoV-2 NSP1 is produced by E.coli expression system and the target gene encoding Met1-Gly180 is expressed with N-His Tag
表达系统（Expression system）
E.coli
种属（Species）
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Accession #
YP_009725297.1
别名（Alternative names)
SARS-CoV 2 nsp1,SARS-CoV 2 Leader protein
预测分子量（Predicted Molecular Mass）
21.94kDa
实际分子量（Actual Molecular Mass）
22-23kDa
纯度（Purity）
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）
Please contact with the lab for this information
制剂（Formulation）
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式（Shipping）
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Please refer to the instraction in the hard copy of COA.
应用（Application）
Immunogen
背景（Background）
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.
Note
For research use only .
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Amily
