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- 产品名称： Research Grade Teprotumumab ( 替妥木单抗 )
- 产品货号： CSD00231
- 货期： 现货
- 价格与订购： 2480
- 数量：
库存： 100
- 规格： 100μg
- 产品信息
- 如何订购
货号（Catalog No.）
CSD00231
通用名INN
Teprotumumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor.8 Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 20163 and was approved by the FDA in January 2020 for the treatment of TED.7 Thyroid eye disease is a potentially debilitating complication of Graves' Disease involving inflammation and tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive surgeries - teprotumumab is the first drug ever approved for the treatment of TED and therefore represents a significant step forward in the treatment this disease.
别名(Alternative names)
RO4858696-000
靶点;物种(Specificity target name;species)
IGF1R/CD221[Homo sapiens]
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
IgG1-nd
分子量(MV)
148000.00 Da
CAS
1036734-93-6
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
产品销售：
E - mail ：
邮 编：
Amily
