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- 产品名称： Anti SARS-CoV-2(2019-nCoV) RBD Neutralizing antibody (AM001414)
- 产品货号： CSMA10328Mo
- 货期： 现货
- 价格与订购： 2880
- 数量：
库存： 100
- 规格：
- 产品信息
- 如何订购
产品名（Product Name）
Anti SARS-CoV-2(2019-nCoV) RBD Neutralizing antibody (AM001414)
货号（Catalog No.）
CSMA10328Mo
描述（description）
Recombinant anti-SARS-CoV-2 RBD antibody is expressed from XtenCHO
特异性（Spcificty）
Recognizes SARS-CoV-2 RBD Protein
亚型（Isotype）
IgG1
克隆性（Clonality）
Monoclonal
别名（Alternative names)
414-1，Anti Spike glycoprotein antibody,Anti 2019-nCoV RBD antibody,Anti 2019-nCoV Spike RBD antibody
偶连物（Conjugation）
Unconjugated
种属反应性（Species reactivity）
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验（Tested applications）
ELISA,Neutralization
免疫原（Immunogen）
Recombinant SARS-CoV-2 RBD protein
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状态（Form）
Liquid
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
储存溶液（Buffer）
PBS,pH7.5
应用实验及稀释比例（Dilution Range）
ELISA:1:5000-1:10000
背景（Background）
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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Note
For research use only .
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