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- 产品名称: Research Grade Placulumab ( 普拉鲁单抗 )
- 产品货号: CSD00297
- 货期: 现货
- 价格与订购: 2480
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
货号(Catalog No.)
CSD00297
通用名INN
Placulumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis.
别名(Alternative names)
ART621,CEP-37247,PN0621
靶点;物种(Specificity target name;species)
TNFSF2/TNF-alpha/TNFA[Homo sapiens]
活性研究(体外/体内研究)(Activity in vitro)
Adalimumab (anti-TNF-alpha) blocks the interaction of TNF with the p55 and p75 cell surface TNF receptors, thereby neutralising the activity of this cytokine. Through its anti-TNF actions, adalimumab reduces concentrations of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, reduces of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, and reduces concentrations of acute phase reactants of inflammation (C-reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-1β mRNA, IL-1 receptor antagonist, IL-6).
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
[V-kappa]2-Fc
CAS
945781-29-3
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .