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  • 产品名称: Anti B2M mouse monoclonal antibody(1F6)
  • 产品货号: CSMA10012Mo
  • 货期: 现货
  • 价格与订购: 980
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 200μg
  • 产品信息
  • 如何订购
    产品名(Product Name)
    Anti B2M mouse monoclonal antibody(1F6)
    货号(Catalog No.)
    CSMA10012Mo
    描述(description)
    B2M, also known as β2-Microglobulin or CDABP92, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M(β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M(β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens.B2M(β2- Microglobulin) is present in free form in various body fluids and as a subunit of histocompatibility antigens on cell surfaces lateral to theα3 chain. Unlikeα3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. In the absence of B2M(β2 microglobulin), very limited amounts of MHC class I (classical and non-classical) molecules can be detected on the surface. In the absence of MHC class I, CD8 T cells, a subset of T cells involved in the development of acquired immunity cannot develop. Low levels of B2M(β2 microglobulin) can indicate non-progression of HIV.
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    亚型(Isotype)
    IgG1
    克隆性(Clonality)
    Monoclonal
    别名(Alternative names)
    B2M,Beta-2-microglobulin
    克隆号(Clone No.)
    1F6
    宿主(Host)
    Mouse
    来源(Source)
    Ascites
    浓度(Concentration)
    Please refer to the instraction in the hard copy of COA.
    偶连物(Conjugation)
    Unconjugated
    种属反应性(Species reactivity)
    Homo sapiens (Human)
    应用实验(Tested applications)
    IHC,ELISA
    免疫原(Immunogen)
    Recombinant protein of full length human beta-2-microglobulin
    icon
    状态(Form)
    Liquid
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    储存溶液(Buffer)
    PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
    Note
    For research use only .