![](/storage/0000/f7486b7c6b600a81c32dfe8bcbbd3484.jpg)
浏览量: 79
- 产品名称: Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
- 产品货号: CSMP00554HU
- 货期: 现货
- 价格与订购: 2880
- 数量:
- 规格:
- 产品信息
- 如何订购
产品名称(Product name)
Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
货号(Catalog#)
CSMP00554HU
icon
icon
描述(description)
A DNA sequence encoding the human F2(Met1-Glu622)with C-terminal His Tag
表达系统(Expression system)
Mammalian cells
iconiconicon 种属(Species)
Homo sapiens (Human)
Accession #
P00734
icon
别名(Alternative names)
Coagulation factor II
实际分子量(Actual Molecular Mass)
85kDa
纯度(Purity)
>90% by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
制剂(Formulation)
Supplied as solution form in PBS, pH7.5/ Supplied as lyophilized from PBS, pH7.5
运输方式(Shipping)
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Please refer to the instraction in the hard copy of COA.icon
应用(Application)
Calibrator or standard in ELISA, WB, IHC and other possible application
icon
icon
iconicon
iconicon
背景(Background)
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC
iconiconiconicon Note
For research use only .