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  • 产品名称: Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
  • 产品货号: CSMP00554HU
  • 货期: 现货
  • 价格与订购: 2880
  • 数量:
    库存: 100
  • 规格:
  • 产品信息
  • 如何订购
    产品名称(Product name)
    Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
    货号(Catalog#)
    CSMP00554HU
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    描述(description)
    A DNA sequence encoding the human F2(Met1-Glu622)with C-terminal His Tag
    表达系统(Expression system)
    Mammalian cells
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    种属(Species)
    Homo sapiens (Human)
    Accession #
    P00734
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    别名(Alternative names)
    Coagulation factor II
    实际分子量(Actual Molecular Mass)
    85kDa
    纯度(Purity)
    >90% by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    制剂(Formulation)
    Supplied as solution form in PBS, pH7.5/ Supplied as lyophilized from PBS, pH7.5
    运输方式(Shipping)
    In general, proteins are shipped out with blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
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    复溶(Reconstitution)
    Please refer to the instraction in the hard copy of COA.icon
    应用(Application)
    Calibrator or standard in ELISA, WB, IHC and other possible application
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    背景(Background)
    Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC
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    Note
    For research use only .