Recombinant Human Caspase 9 protein

>90% as determined by SDS-PAGE

Please contact with the lab for this information.

A DNA sequence encoding the human Caspase 9 (Lys100-270Thr) was fused with SUMO tag

P55211

E.coli

Homo sapiens (Human)

34.58 kDa

Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Caspase-9,CASP-9,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,APAF-3,ICE-like apoptotic protease 6,ICE-LAP6,CASP9,MCH6

For research use only .