
浏览量: 69
- 产品名称: Recombinant Human SIRT6 protein
- 产品货号: CSP00181
- 货期: 现货
- 价格与订购: 1800
- 数量:
- 规格: 50μg 100μg 1mg
- 产品信息
- 如何订购
概述(Summary)
英文全称
Recombinant Human SIRT6 protein
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白构建(Construction)
A DNA sequence encoding the human SIRT6 (Met1-Ser355) was fused with His tag
Accession #
Q8N6T7
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
预测分子量(Predicted Molecular Mass)
39.96 kDa
制剂(Formulation)
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景(Background)
背景介绍
Sirtuin 6 (SIRT6) is a nicotinamide adenine dinucleotide(+) (NAD(+)) dependent enzyme and stress response protein. SIRT6 has several different functions in multiple different molecular pathways related to DNA repair, glycolysis, gluconeogenesis, tumorigenesis, neurodegeneration, cardiac hypertrophic responses, and more. SIRT6 is a main regulator of metabolism and lifespan and its importance has been implicated in the prevention against aging-related diseases. SIRT6 depletion enhanced chemosensitivity of human hepatoma cells by downregulating MDR1 expression through suppressing C/EBPbeta. SIRT6 may serve as a novel target to enhance chemosensitivity in HCC cells.
分子别名(Alternative Names)
NAD-dependent protein deacetylase sirtuin-6,Regulatory protein SIR2 homolog 6,SIR2-like protein 6.
Note
For research use only .