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  • 产品名称: Recombinant Human IGF1 protein
  • 产品货号: CSP00241
  • 货期: 现货
  • 价格与订购: 1800
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 1mg
  • 产品信息
  • 如何订购
    概述(Summary)
    英文全称
    Recombinant Human IGF1 protein
    纯度(Purity)
    >90% as determined by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白构建(Construction)
    A DNA sequence encoding the human IGF1 (Gly49-Ala118) was fused with His tag
    Accession #
    P05019
    表达宿主(Host)
    E.coli
    种属(Species)
    Homo sapiens (Human)
    预测分子量(Predicted Molecular Mass)
    9.82 kDa
    制剂(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    运输方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    复溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介绍
    IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
    分子别名(Alternative Names)
    Insulin-like growth factor I,IGF-I,Mechano growth factor,MGF,Somatomedin-C.
    Note
    For research use only .