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- 产品名称： Recombinant Human CXCR4 protein
- 产品货号： CSP00336
- 货期： 现货
- 价格与订购： 1800
- 数量：
库存： 100
- 规格： 50μg 100μg 1mg
- 产品信息
- 如何订购
概述（Summary）
英文全称
Recombinant Human CXCR4 protein
纯度（Purity）
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白构建（Construction）
A DNA sequence encoding the human CXCR4 (Ser217-Ser352) was fused with His tag
Accession #
P61073
表达宿主（Host）
E.coli
种属（Species）
Homo sapiens (Human)
预测分子量（Predicted Molecular Mass）
15.36 kDa
制剂（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介绍
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.
(Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1/HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus
(Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1/HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus
分子别名（Alternative Names）
C-X-C chemokine receptor type 4,CXC-R4,CXCR-4,FB22,Fusin,HM89,LCR1,Leukocyte-derived seven transmembrane domain receptor,LESTR,Lipopolysaccharide-associated protein 3,LAP-3,LPS-associated protein 3,NPYRL,Stromal cell-derived factor 1 receptor,SDF-1 receptor,CD184.
Note
For research use only .
地 址：
产品销售：
E - mail ：
邮 编：
Amily
