159-2642-3062 027-65317797
服务热线(工作日:9:00-17:30)

浏览量: 64

  • 产品名称: Recombinant Human PAK1 protein
  • 产品货号: CSP00647
  • 货期: 现货
  • 价格与订购: 1800
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 1mg
  • 产品信息
  • 如何订购
    概述(Summary)
    英文全称
    Recombinant Human PAK1 protein
    纯度(Purity)
    >90% as determined by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白构建(Construction)
    A DNA sequence encoding the human PAK1 (Glu252-Cys501) was fused with His tag
    Accession #
    Q13153
    表达宿主(Host)
    E.coli
    种属(Species)
    Homo sapiens (Human)
    预测分子量(Predicted Molecular Mass)
    27.85 kDa
    制剂(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    运输方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    复溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介绍
    P21-activated kinase-1 (PAK1) is an enzyme associated with multiple metabolic networks and different types of cancers.PAK1 (RAC/CDC42-activated kinase 1) is the major oncogenic/ageing kinase, and its dysfunction extends the healthy lifespan of C. elegans by activating HSP16 gene.The p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1) expression appears to be predictive of prognosis in various solid tumors.PAK1 expression may be a predictive marker of overall survival and disease-specific survival in patients with solid tumors.p21-Activated kinase 1 (PAK1) has attracted much attention as a potential therapeutic target due to its central role in many oncogenic signaling pathways, its frequent dysregulation in cancers and neurological disorders, and its tractability as a target for small-molecule inhibition.
    分子别名(Alternative Names)
    Serine/threonine-protein kinase PAK 1,Alpha-PAK,p21-activated kinase 1,PAK-1,p65-PAK.
    Note
    For research use only .