159-2642-3062 027-65317797
服务热线(工作日:9:00-17:30)

浏览量: 57

  • 产品名称: Recombinant Human PLA2G4A protein
  • 产品货号: CSP00654
  • 货期: 现货
  • 价格与订购: 1800
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 1mg
  • 产品信息
  • 如何订购
    概述(Summary)
    英文全称
    Recombinant Human PLA2G4A protein
    纯度(Purity)
    >90% as determined by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白构建(Construction)
    A DNA sequence encoding the human PLA2G4A (Met1-Ser178) was fused with His tag
    Accession #
    P47712
    表达宿主(Host)
    E.coli
    种属(Species)
    Homo sapiens (Human)
    预测分子量(Predicted Molecular Mass)
    21.8 kDa
    制剂(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    运输方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    复溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介绍
    Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response. Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production. Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids. Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway. In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position. This hydrolysis is not stereospecific. Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides . Has O-acyltransferase activity. Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis.
    分子别名(Alternative Names)
    Cytosolic phospholipase A2,cPLA2,Phospholipase A2 group IVA,Phospholipase A2,Phosphatidylcholine 2-acylhydrolase,Lysophospholipase.
    Note
    For research use only .