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  • 产品名称: Recombinant Human KNG1 protein
  • 产品货号: CSP00835
  • 货期: 现货
  • 价格与订购: 1800
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 1mg
  • 产品信息
  • 如何订购
    概述(Summary)
    英文全称
    Recombinant Human KNG1 protein
    纯度(Purity)
    >90% as determined by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白构建(Construction)
    A DNA sequence encoding the human KNG1 (Arg58-Leu176) was fused with His tag
    Accession #
    P01042
    表达宿主(Host)
    E.coli
    种属(Species)
    Homo sapiens (Human)
    预测分子量(Predicted Molecular Mass)
    14.5 kDa
    制剂(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    运输方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    复溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介绍
    Kininogen-1, also known as high molecular weight kininogen, williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1 and BDK, is a secreted protein which contains threecystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of thekininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients, in fact, had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis.
    分子别名(Alternative Names)
    Kininogen-1,Alpha-2-thiol proteinase inhibitor,Fitzgerald factor,High molecular weight kininogen,HMWK,Williams-Fitzgerald-Flaujeac factor.
    Note
    For research use only .