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- 产品名称： Recombinant Human MYOC protein
- 产品货号： CSP01059
- 货期： 现货
- 价格与订购： 1800
- 数量：
库存： 100
- 规格： 50μg 100μg 1mg
- 产品信息
- 如何订购
概述（Summary）
英文全称
Recombinant Human MYOC protein
纯度（Purity）
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白构建（Construction）
A DNA sequence encoding the human MYOC (Ala224-Tyr471) was fused with His tag
Accession #
Q99972
表达宿主（Host）
E.coli
种属（Species）
Homo sapiens (Human)
预测分子量（Predicted Molecular Mass）
27.95 kDa
制剂（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介绍
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC and GLC1A, is a protein which contains oneolfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma. Defects in Myocilin / MYOC may contribute to primary congenital glaucoma type 3A (GLC3A). Defects in MYOC may also contribute to this phenotype via digenic inheritance. GLC3A is an autosomal recessive form of primary congenital glaucoma (PCG). PCG is characterized by marked increase of intraocular pressure at birth or early choldhood, large ocular globes (buphthalmos) and corneal edema.
分子别名（Alternative Names）
Myocilin,Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein.
Note
For research use only .
地 址：
产品销售：
E - mail ：
邮 编：
Amily
