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- 产品名称： Recombinant Human S100A16 protein
- 产品货号： CSP01460
- 货期： 现货
- 价格与订购： 1800
- 数量：
库存： 100
- 规格： 50μg 100μg 1mg
- 产品信息
- 如何订购
概述（Summary）
英文全称
Recombinant Human S100A16 protein
纯度（Purity）
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白构建（Construction）
A DNA sequence encoding the human S100A16 (Ser2-Ser103) was fused with His tag
Accession #
Q96FQ6
表达宿主（Host）
E.coli
种属（Species）
Homo sapiens (Human)
预测分子量（Predicted Molecular Mass）
12.92 kDa
制剂（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介绍
S1A16 is a member of S1 protein super family that carries calcium-binding EF-hand motifs. S1 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S1A16 expression was found to be astrocyte-specific. The S1A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S1A16 in the apo state has been obtained both in the solid state and in solution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S1A16 was also calculated in the calcium(II)-bound form. Differently from most S1 proteins, the conformational rearrangement upon calcium binding is minor. Immunoprecipitation analysis revealed that S1A16 could physically interact with tumor suppressor protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S1A16 led to the inhibition or activation of the expression of p53-responsive genes, respectively. S1A16 protein is a novel adipogenesis-promoting factor.
分子别名（Alternative Names）
AAG13 Protein, Human; DT1P1A7 Protein, Human; MGC17528 Protein, Human; S100F Protein, Human
Note
For research use only .
地 址：
产品销售：
E - mail ：
邮 编：
Amily
