Recombinant Human CLU protein

>90% as determined by SDS-PAGE

Please contact with the lab for this information.

A DNA sequence encoding the human CLU (Ser228-Glu449) was fused with His tag

P10909

E.coli

Homo sapiens (Human)

27.4 kDa

Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Clusterin, also known as complement-associated protein SP-4, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

Clusterin,Aging-associated gene 4 protein,Apolipoprotein J,Apo-J,Complement cytolysis inhibitor,CLI,Complement-associated protein SP-40,40,Ku70-binding protein 1,NA1/NA2,Sulfated glycoprotein 2,SGP-2,Testosterone-repressed prostate message 2,TRPM-2,ApoJalpha,Complement cytolysis inhibitor a chain,ApoJbeta,Complement cytolysis inhibitor b chain.

For research use only .