Recombinant Human LGALS8 protein

>90% as determined by SDS-PAGE

Please contact with the lab for this information.

A DNA sequence encoding the human LGALS8 (Met2-Trp317) was fused with His tag

O00214

E.coli

Homo sapiens (Human)

34.7 kDa

Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture.Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52.Required to restrict infection of bacterial invasion such as S.typhimurium . Also required to restrict infection of Picornaviridae viruses.Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.

Galectin-8,Gal-8,Po66 carbohydrate-binding protein,Po66-CBP,Prostate carcinoma tumor antigen 1,PCTA-1.

For research use only .