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- 产品名称: Recombinant human Amyloid beta(aa1-42) protein
- 产品货号: CSP11005
- 货期: 现货
- 价格与订购: 1800
- 数量:
- 规格: 50μg 100μg 1mg
- 产品信息
- 如何订购
概述(Summary)
英文全称
Recombinant human Amyloid beta(aa1-42) protein
纯度(Purity)
>95%
Accession #
P05067
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
背景(Background)
背景介绍
Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
分子别名(Alternative Names)
Abeta; Amyloid beta; beta-Amyloid Peptide