Actin depolymerizing factor, ADF, AGEL,GSN

Rabbit Polyclonal   Antibody 

IgG

Antigen Affinity Purification 

ELISA, WB, IP

80kDa

80kDa

Human,Mouse,Rat,Zebra fish 

Recombinant Human Gelsolin protein expressed by E.Coli

PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 

Store at -20℃. Do not aliquot 

WB: 1:1000-2000IP: 1:5000-10000IF: 1:100-200 

Gelsolin (GSN) is an actin binding protein that regulates actin-severing/depolymerizing in a calcium dependent manner, and acts as a multifunctional regulator for cell metabolism and survival. Gelsolin exists in two isoforms: a cytoplasmic gelsolin (cGSN; 80-90 kDa) and a plasma gelsolin (pGSN; 93 kDa), differing at N terminal residues. Decreased levels of pGSN are strongly associated with human diseases, such as, acute liver injury, major trauma, myocardial infarction, inflammation, lung injury, rheumatoid arthritis, hemodialysis, multiple sclerosis, Alzheimer's disease..

For research use only .