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- 产品名称： Anti STK11 Mouse Monoclonal Antibody
- 产品货号： CS26158
- 货期： 现货
- 价格与订购： 2800
- 数量：
库存： 100
- 规格： 100μl 200μl
- 产品信息
- 如何订购
Catalog Number
CS26158
Gene Symbol
STK11, LKB1, PJS, hLKB1
Description
Anti STK11 Mouse Monoclonal Antibody
Background
Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer.
Immunogen
A synthetic peptide from the internal region of STKwhich includes the mutation of P281L, human origin.
Applications
ELISA, WB, IHC
Recommended Dilutions
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:200
Concentration
0.5mg/ml
Host
mouse
Format
Liquid
Clonality
Monoclonal
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
Recognizes P281L mutated, but not wild-type STK11 of vertebrates.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
Immunofluorescence:
Immunofluorescence of cells expressing STK11 proteins with Anti STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP STK11 (WT) plasmid (left column) or pCDNA3-GFP STK11 (P281L) plasmid (right column), then fixed and stained with Anti STK11 (P281L) monoclonal antibody (Cat. #CS26158).
Note
For research use only .
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