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- 产品名称： Anti BRCA1(1720-1863) Mouse Monoclonal Antibody
- 产品货号： CS26351-2
- 货期： 现货
- 价格与订购： 2800
- 数量：
库存： 100
- 规格： 100μl 200μl
- 产品信息
- 如何订购
Catalog Number
CS26351-2
Gene Symbol
BRCA1,BRCC1,IRIS,PNCA4,PPP1R53,PSCP
Description
Anti BRCA1(1720-1863) Mouse Monoclonal Antibody
Background
BRCA1 is normally expressed in cells of breast and other tissues,where it helps repair damaged DNA or destroy cells if DNA cannot be repaired. It is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double-strand breaks. If BRCA1 itself is damaged by a BRCA1 mutation,damaged DNA is not repaired properly,and this increases the risk for breast cancer.
Immunogen
Purified BRCA1(1720-1863) protein, human origin.
Applications
ELISA, WB, IHC
Recommended Dilutions
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration
1 mg/ml
Host
mouse
Format
Liquid
Clonality
Monoclonal
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
Recognizes BRCA1(1720-1863) of vertebrates.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
Western blot
Western blot analysis of recombinant BRCA1(1-120) and BRCA1(1720-1863) proteins. Purified His-tagged BRCA1 1-120) protein (lane1) and corresponding His-tagged BRCA1(1720-1831) (lane2) were blotted with Anti BRCA1(1720-1863) monoclonal antibody (Cat. #CS26351-2).
Immunofluorescence
Immunofluorescence of cells expressing BRCA1(1720-1863)protein with Anti BRCA1(1720-1863) antibody. HEK293T cells was transfected with pCDNA3-GFP-BRCA1(1720-1863) plasmid, then fixed and stained with Anti BRCA1(1720-1863) monoclonal antibody (Cat. #CS26351-2).
Note
For research use only .
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