CS26133

GRB7 

anti GRB7 Mouse Monoclonal Antibody 

Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in breast cancers. Grb7 is over-expressed in testicular germ cell tumors, esophageal cancers, and gastric cancers. There are clues that it involved in cell migration and metastatic progression of human esophageal carcinomas. 

 Purified GRB7 protein, human origin. 

ELISA, WB, IHC 

0.5 mg/ml 

mouse 

Liquid 

Monoclonal  

Purified from ascites 

no 

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol 

Recognizes GRB7 of vertebrates. 

Store at -20°C. Avoid freeze / thaw cycles 

For research use only .