Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye that binds strongly to DNA and RNA, and is widely used as a retrograde neuronal tracer, while also acting as a potent inhibitor of cellular ribonucleases, making it a versatile research reagent for neuroanatomical tracing, nucleic acid labeling, and studies of RNA stability and degradation.

It is found that the trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) permits the recovery of mRNA after polysome released with Nonidet P-40 (NP-40). Sucrose gradient analysis of detergent-lysed postnuclear supernates is used to analyze the size distribution of NP-40-released polysomes .

在接种绵羊红细胞 (SRBC) 的小鼠模型中，评估了Hydroxystilbamidine bis(methanesulfonate) 对免疫反应的影响。给予该化合物与溶血空斑形成细胞 (PFC) 数量的减少相关

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