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- 产品名称: MDA Lysine Rabbit Rabbit PAb
- 产品货号: CS3091
- 货期: 现货
- 价格与订购: 2398
- 数量:
- 规格: 100μl 1ml
- 产品信息
- 如何订购
Attribute
Rabbit Polyclonal Antibody
Isotype
IgG
Purity
Antigen Affinity Purification
Application
WB, IP, ELISA
Reactivity
MDA aducts
Immunogen
MDA protein
Buffer
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2
Storage
Store at -20℃. Do not aliquot
Recommended Dilution
WB: 1:1000-2000 IP: 1:5000-10000
Background
Malondialdehyde (MDA) and acetaldehyde (AA) react synergistically to form hybrid malondialdehyde–acetaldehyde (MAA) adducts . MAA adducts are unique among aldehyde–protein adducts in their stability, potent immunogenicity, ability to alter protein regulatory elements (i.e.,ε-amino lysine residue), and dose-dependent direct cellular toxicity . These properties of MAA adducts represent one pathogenic mechanism by which classical risk factors for cardiovascular disease(i.e., hypertension, hyperlipidemia, diabetes, and tobacco use) may result in inflammation and lead to specific clinical entities such as atherosclerosis.
Note
For research use only .